PerioBrite is Gluten-Free Fluoride Free Soy-Free/Vegetarian contains no Sodium-Lauryl-Sulfate. Periobrite has No Artificial Sweeteners, No Artificial Preservatives, Naturally Brightens Soothes & Refreshes with All Natural Ingredients ...... it is Suitable for Entire Family. Smile Naturally! Cruelty Free – Not Tested on Animals Holistically Balanced Dentist formulated PerioBrite Natural Brightening Toothpaste contains Phytoplenolin, a patented herbal extract that has been shown in independent laboratory studies to promote cell vitality. Soothing wildcrafted herbs, well-know for their cleansing action, are combined with CoQ10, Folic Acid, Oregano, Cinnamon and Clove to promote tissue and gum wellness. PerioBrite naturally brightens teeth while leaving your breath fresh and clean energizing your whole mouth with cool, sparkling, minty fresh sensation.